Dataset Information

Correspondence Between Perceived Pubertal Development and Hormone Levels in 9-10 Year-Olds From the Adolescent Brain Cognitive Development Study.

ABSTRACT:

Aim

To examine individual variability between perceived physical features and hormones of pubertal maturation in 9-10-year-old children as a function of sociodemographic characteristics.

Methods

Cross-sectional metrics of puberty were utilized from the baseline assessment of the Adolescent Brain Cognitive Development (ABCD) Study-a multi-site sample of 9-10 year-olds (n = 11,875)-and included perceived physical features via the pubertal development scale (PDS) and child salivary hormone levels (dehydroepiandrosterone and testosterone in all, and estradiol in females). Multi-level models examined the relationships among sociodemographic measures, physical features, and hormone levels. A group factor analysis (GFA) was implemented to extract latent variables of pubertal maturation that integrated both measures of perceived physical features and hormone levels.

Results

PDS summary scores indicated more males (70%) than females (31%) were prepubertal. Perceived physical features and hormone levels were significantly associated with child's weight status and income, such that more mature scores were observed among children that were overweight/obese or from households with low-income. Results from the GFA identified two latent factors that described individual differences in pubertal maturation among both females and males, with factor 1 driven by higher hormone levels, and factor 2 driven by perceived physical maturation. The correspondence between latent factor 1 scores (hormones) and latent factor 2 scores (perceived physical maturation) revealed synchronous and asynchronous relationships between hormones and concomitant physical features in this large young adolescent sample.

Conclusions

Sociodemographic measures were associated with both objective hormone and self-report physical measures of pubertal maturation in a large, diverse sample of 9-10 year-olds. The latent variables of pubertal maturation described a complex interplay between perceived physical changes and hormone levels that hallmark sexual maturation, which future studies can examine in relation to trajectories of brain maturation, risk/resilience to substance use, and other mental health outcomes.

SUBMITTER: Herting MM

PROVIDER: S-EPMC7930488 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Publications

Correspondence Between Perceived Pubertal Development and Hormone Levels in 9-10 Year-Olds From the Adolescent Brain Cognitive Development Study.

Herting Megan M MM Uban Kristina A KA Gonzalez Marybel Robledo MR Baker Fiona C FC Kan Eric C EC Thompson Wesley K WK Granger Douglas A DA Albaugh Matthew D MD Anokhin Andrey P AP Bagot Kara S KS Banich Marie T MT Barch Deanna M DM Baskin-Sommers Arielle A Breslin Florence J FJ Casey B J BJ Chaarani Bader B Chang Linda L Clark Duncan B DB Cloak Christine C CC Constable R Todd RT Cottler Linda B LB Dagher Rada K RK Dapretto Mirella M Dick Anthony S AS Dosenbach Nico N Dowling Gayathri J GJ Dumas Julie A JA Edwards Sarah S Ernst Thomas T Fair Damien A DA Feldstein-Ewing Sarah W SW Freedman Edward G EG Fuemmeler Bernard F BF Garavan Hugh H Gee Dylan G DG Giedd Jay N JN Glaser Paul E A PEA Goldstone Aimee A Gray Kevin M KM Hawes Samuel W SW Heath Andrew C AC Heitzeg Mary M MM Hewitt John K JK Heyser Charles J CJ Hoffman Elizabeth A EA Huber Rebekah S RS Huestis Marilyn A MA Hyde Luke W LW Infante M Alejandra MA Ivanova Masha Y MY Jacobus Joanna J Jernigan Terry L TL Karcher Nicole R NR Laird Angela R AR LeBlanc Kimberly H KH Lisdahl Krista K Luciana Monica M Luna Beatriz B Maes Hermine H HH Marshall Andrew T AT Mason Michael J MJ McGlade Erin C EC Morris Amanda S AS Nagel Bonnie J BJ Neigh Gretchen N GN Palmer Clare E CE Paulus Martin P MP Potter Alexandra S AS Puttler Leon I LI Rajapakse Nishadi N Rapuano Kristina K Reeves Gloria G Renshaw Perry F PF Schirda Claudiu C Sher Kenneth J KJ Sheth Chandni C Shilling Paul D PD Squeglia Lindsay M LM Sutherland Matthew T MT Tapert Susan F SF Tomko Rachel L RL Yurgelun-Todd Deborah D Wade Natasha E NE Weiss Susan R B SRB Zucker Robert A RA Sowell Elizabeth R ER

Frontiers in endocrinology 20210218

<h4>Aim</h4>To examine individual variability between perceived physical features and hormones of pubertal maturation in 9-10-year-old children as a function of sociodemographic characteristics.<h4>Methods</h4>Cross-sectional metrics of puberty were utilized from the baseline assessment of the Adolescent Brain Cognitive Development (ABCD) Study-a multi-site sample of 9-10 year-olds (n = 11,875)-and included perceived physical features <i>via</i> the pubertal development scale (PDS) and child sal ...[more]

PMID: 33679599

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Project description:BACKGROUND:Sugar-sweetened drinks (SSDs) are known to be cariogenic, but this association has not been well investigated in population-based repeated cross-sectional studies in recent years. Therefore, this study examined whether SSD intake is associated with higher caries experience in 10- and 15-year-olds. METHODS:The study sample included participants from the Munich study centre of two birth cohorts with data on non-cavitated caries lesions (NCCL/S), caries experience (DMF/S index), overall caries burden (DMF?+?NCCL/S) and SSD intake. In total, 915 and 996 children were included from the 10- and 15-year follow-ups, respectively. Intake (g/day) of SSDs, comprising cola, lemonade, ice-tea, sport/energy drinks, fruit squashes and nectars, was calculated from food frequency questionnaires. For analyses, the SSD intake was converted into portions (250?ml/day). Multiple logistic regression and prospective analysis models were performed to test associations between SSD intake and various definitions of caries, adjusting for sex, parental education, body mass index (BMI) categories, study cohort, plaque-affected sextants, mode of SSD consumption, energy content of SSDs, and total energy intake. RESULTS:The mean overall caries burden at 10 and 15?years of age was 1.81 (SD: 2.71) and 6.04 (SD: 8.13), respectively. The average consumption of SSDs at the 10- and 15-year follow-ups was 0.48 (SD: 0.85) and 0.83 (SD 1.40) portions/day, respectively. After adjusting for confounders, in 10-year-olds, SSD intake was significantly associated with higher caries experience based on the indices DMF/S (adjusted odds ratio: 1.29; 95% CI: 1.06-1.57), NCCL/S (1.24; 1.03-1.49) and DMF?+?NCCL/S (1.27; 1.05-1.55). At the 15-year follow-up, SSD consumption was significantly associated with increased DMF/S index (1.12; 1.01-1.25) only. Prospective model associating 10-year SSD intake with 15-year caries experience was not significant. CONCLUSIONS:SSD intake significantly increases the caries burden in 10-year-olds, with attenuated effects in 15-year-olds. To prevent caries, SSD consumption should be reduced, especially in children and adolescents.

Dataset Information

Correspondence Between Perceived Pubertal Development and Hormone Levels in 9-10 Year-Olds From the Adolescent Brain Cognitive Development Study.

Aim

Methods

Results

Conclusions

Publications

Correspondence Between Perceived Pubertal Development and Hormone Levels in 9-10 Year-Olds From the Adolescent Brain Cognitive Development Study.

Similar Datasets

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