Ontology highlight
ABSTRACT:
SUBMITTER: Wu M
PROVIDER: S-EPMC7931217 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Wu Minhua M Lan Hui H Ye Zhongwei Z Wang Yonghui Y
FEBS open bio 20210221 3
Pregnancy zone protein (PZP), a member of the proteinase inhibitor I39 (-2-macroglobulin) family of proteins, is involved in the initiation and development of various tumors. The gene encoding PZP is hypermethylated and expressed at low levels in hepatocellular carcinoma (HCC) tissue and cells, but the function of PZP in HCC cells remains unclear. Here, we analyzed DNA methylation and mRNA expression of HCC in The Cancer Genome Atlas Liver Hepatocellular Carcinoma dataset. We identified 10 methy ...[more]