Ontology highlight
ABSTRACT:
SUBMITTER: Lai HY
PROVIDER: S-EPMC7931828 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Lai Hong-Yue HY Tsai Hsin-Hwa HH Yen Chia-Jui CJ Hung Liang-Yi LY Yang Ching-Chieh CC Ho Chung-Han CH Liang Hsin-Yin HY Chen Feng-Wei FW Li Chien-Feng CF Wang Ju-Ming JM
Frontiers in cell and developmental biology 20210121
Despite the activation of autophagy may enable residual cancer cells to survive and allow tumor relapse, excessive activation of autophagy may eventually lead to cell death. However, the details of the association of autophagy with primary resistance in hepatocellular carcinoma (HCC) remain less clear. In this study, cohort analysis revealed that HCC patients receiving sorafenib with HBV had higher mortality risk. We found that high epidermal growth factor receptor (EGFR) expression and activity ...[more]