Independent predictors of acute kidney injury in patients with acute coronary syndrome after percutaneous coronary intervention.

ABSTRACT:

Introduction

High residual platelet reactivity (RPR) in patients after percutaneous coronary intervention (PCI) receiving antiplatelet agents has been associated with a high risk of developing acute kidney injury (AKI).

Study aim

This study aimed at identification of independent prognostic predictors of AKI risk in patients with acute coronary syndrome (ACS) after PCI.

Study design, setting and patients

This was a prospective single-center clinical trial that included 155 patients (n = 119 without AKI, n = 36 with AKI, mean age 64.0±10.6 years, of whom 74.2% were males), who underwent PCI with stenting. We prospectively evaluated RPR using optical aggregometry. Development of AKI was the primary endpoint.

Results

Acute renal dysfunction was observed in 36 patie

SUBMITTER: Zhunuspekova A 

PROVIDER: S-EPMC7932092 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature