Ontology highlight
ABSTRACT:
SUBMITTER: Brault V
PROVIDER: S-EPMC7932094 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
PLoS computational biology 20210304 3
We propose an analysis and applications of sample pooling to the epidemiologic monitoring of COVID-19. We first introduce a model of the RT-qPCR process used to test for the presence of virus in a sample and construct a statistical model for the viral load in a typical infected individual inspired by large-scale clinical datasets. We present an application of group testing for the prevention of epidemic outbreak in closed connected communities. We then propose a method for the measure of the pre ...[more]