Identification and Validation of a Novel Six-Gene Prognostic Signature of Stem Cell Characteristic in Colon Cancer.
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ABSTRACT:
SUBMITTER: Liang Y
PROVIDER: S-EPMC7933554 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Identification and Validation of a Novel Six-Gene Prognostic Signature of Stem Cell Characteristic in Colon Cancer.
Liang Yichao Y Su Qi Q Wu Xin X
Frontiers in oncology 20210219
Cancer stem cells play crucial roles in the development of colon cancer (COAD). This study tried to explore new markers for predicting the prognosis of colon cancer based on stem cell-related genes. In our study, 424 COAD samples from TCGA were divided into three subtypes based on 412 stem cell-related genes; there were significant differences in prognosis, clinical characteristics, and immune scores between these subtypes. 694 genes were screened between subgroups. Subsequently a six-gene signa ...[more]
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