Ontology highlight
ABSTRACT:
SUBMITTER: Sidisky JM
PROVIDER: S-EPMC7935490 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
eLife 20210305
Maintaining synaptic structure and function over time is vital for overall nervous system function and survival. The processes that underly synaptic development are well understood. However, the mechanisms responsible for sustaining synapses throughout the lifespan of an organism are poorly understood. Here, we demonstrate that a previously uncharacterized gene, <i>CG31475</i>, regulates synaptic maintenance in adult <i>Drosophila</i> NMJs. We named <i>CG31475 mayday</i> due to the progressive l ...[more]