Ontology highlight
ABSTRACT:
SUBMITTER: Khan MI
PROVIDER: S-EPMC7938794 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Khan Mahamad Irfanulla MI Cs Prashanth P Srinath Narasimha Murthy NM
Global medical genetics 20201201 4
Orofacial clefts (OFCs) are the most common congenital birth defects in humans and immediately recognized at birth. The etiology remains complex and poorly understood and seems to result from multiple genetic and environmental factors along with gene-environment interactions. It can be classified into syndromic (30%) and nonsyndromic (70%) clefts. Nonsyndromic OFCs include clefts without any additional physical or cognitive deficits. Recently, various genetic approaches, such as genome-wide asso ...[more]