Dataset Information

A high basal metabolic rate is an independent predictor of stone recurrence in obese patients.

ABSTRACT:

Purpose

Basal metabolic rate (BMR) is an indicator of overall body metabolism and may portend unique aberrations in urine physico-chemistry and stone recurrence. The present study examined the effect of predicted BMR on 24 hours urinary metabolic profiles and stone recurrence in obese stone patients.

Materials and methods

Data from 308 obese patients (body mass index [BMI] ≥30 kg/m²) diagnosed with urinary stone disease between 2003 and 2015 were analyzed retrospectively. BMR was calculated using the Harris-Benedict equation, and patients were classified into two predicted BMR categories (<1,145 kcal/day, ≥1,145 kcal/day). Urinary metabolic parameters and risk of stone recurrence were compared between the two groups.

Results

The high BMR group was more likely to be younger and female, and to have a high BMI and lower incidence of diabetes than the low BMR group (each p<0.05). There was a positive correlation between BMR and 24 hours urinary sodium, uric acid, and phosphate excretion. The amounts of stone-forming constituents such as calcium and uric acid were significantly higher in the high BMR group. Kaplan-Meier estimates showed that the high BMR group had a significantly shorter stone recurrence-free period than the low BMR group (log-rank test, p<0.001). Multivariate Cox regression analyses revealed that predicted BMR was an independent factor of stone recurrence (hazard ratio, 2.759; 95% confidence interval, 1.413-5.386; p=0.003).

Conclusions

BMR may be an easily measured parameter that can be used to identify risk of stone recurrence in obese stone patients.

SUBMITTER: Kang HW

PROVIDER: S-EPMC7940852 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature

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Publications

A high basal metabolic rate is an independent predictor of stone recurrence in obese patients.

Kang Ho Won HW Seo Sung Pil SP Lee Hee Youn HY Kim Kyeong K Ha Yun Sok YS Kim Won Tae WT Kim Yong June YJ Yun Seok Joong SJ Kim Wun Jae WJ Lee Sang Cheol SC

Investigative and clinical urology 20210301 2

<h4>Purpose</h4>Basal metabolic rate (BMR) is an indicator of overall body metabolism and may portend unique aberrations in urine physico-chemistry and stone recurrence. The present study examined the effect of predicted BMR on 24 hours urinary metabolic profiles and stone recurrence in obese stone patients.<h4>Materials and methods</h4>Data from 308 obese patients (body mass index [BMI] ≥30 kg/m²) diagnosed with urinary stone disease between 2003 and 2015 were analyzed retrospectively. BMR was ...[more]

PMID: 33660447

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Dataset Information

A high basal metabolic rate is an independent predictor of stone recurrence in obese patients.

Purpose

Materials and methods

Results

Conclusions

Publications

A high basal metabolic rate is an independent predictor of stone recurrence in obese patients.

Similar Datasets

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