Habitual consumption of alcohol with meals and lung cancer: a Mendelian randomization study.

ABSTRACT:

Background

The objective of this study was to determine the causal relationship between habitual alcohol consumption with meals and lung cancer.

Methods

Public genetic summary data from two large consortia [the Neale Lab and the International Lung Cancer Consortium (ILCCO)] were used for analysis. As the instrumental variables of habitual alcohol consumption with meals, data on genetic variants were retrieved from Neale Lab. Additionally, genetic data from other consortia [Global Lipid Genetics Consortium (GLGC), Tobacco, Alcohol and Genetics (TAG), Genetic Investigation of Anthropocentric Traits (GIANT)] were utilized to determine whether alcohol could causally alter some general risk factors for lung cancer. The primary outcome was the risk of lung cancer (11,348 cases and

SUBMITTER: Chen C 

PROVIDER: S-EPMC7940946 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature