Ontology highlight
ABSTRACT:
SUBMITTER: Lian X
PROVIDER: S-EPMC7942227 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Lian Xiaolei X Bond J Steffan JS Bharathy Narendra N Boudko Sergei P SP Pokidysheva Elena E Shern Jack F JF Lathara Melvin M Sasaki Takako T Settelmeyer Teagan T Cleary Megan M MM Bajwa Ayeza A Srinivasa Ganapati G Hartley Christopher P CP Bächinger Hans Peter HP Mansoor Atiya A Gultekin Sakir H SH Berlow Noah E NE Keller Charles C
Frontiers in oncology 20210223
Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood with a propensity to metastasize. Current treatment for patients with RMS includes conventional systemic chemotherapy, radiation therapy, and surgical resection; nevertheless, little to no improvement in long term survival has been achieved in decades-underlining the need for target discovery and new therapeutic approaches to targeting tumor cells or the tumor microenvironment. To evaluate cross-species sarcoma extracellu ...[more]