Background characteristics and anticoagulant usage patterns of elderly non-valvular atrial fibrillation patients in the ANAFIE registry: a prospective, multicentre, observational cohort study in Japan.

ABSTRACT:

Objective

To explore anticoagulant usage patterns stratified by stroke and bleeding risk in elderly patients with non-valvular atrial fibrillation (NVAF).

Design

Prospective, multicentre, observational cohort study.

Setting

The real-world All Nippon AF In the Elderly (ANAFIE) registry.

Participants

Japanese patients aged ≥75 years with NVAF (n=32 726).

Outcome measures

The distribution of stroke and bleeding risk scores, and the selection of anticoagulant regimen for patients at high stroke and bleeding risk.

Results

Overall, 18 185 (55.6%) patients had a high risk of stroke (CHADS₂ score ≥3). Of these, 12 561 (38.4% of the total ANAFIE population) had a low bleeding risk (HAS-BLED ≤2) and 5624 (17.2%) had a high bleeding risk (HAS-BLED

SUBMITTER: Yasaka M 

PROVIDER: S-EPMC7942257 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature