Intergenerational Transmission of Cortical Sulcal Patterns from Mothers to their Children.

ABSTRACT: Intergenerational effects are described as the genetic, epigenetic, as well as pre- and postnatal environmental influence parents have on their offspring's behavior, cognition, and brain. During fetal brain development, the primary cortical sulci emerge with a distinctive folding pattern that are under strong genetic influence and show little change of this pattern throughout postnatal brain development. We examined intergenerational transmission of cortical sulcal patterns by comparing primary sulcal patterns between children (N = 16, age 5.5 ± 0.81 years, 8 males) and their biological mothers (N = 15, age 39.72 ± 4.68 years) as well as between children and unrelated adult females. Our graph-based sulcal pattern comparison method detected stronger sulcal pattern similarity for child-mothe

SUBMITTER: Ahtam B 

PROVIDER: S-EPMC7945013 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature