Ontology highlight
ABSTRACT:
SUBMITTER: Piper K
PROVIDER: S-EPMC7945033 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Frontiers in oncology 20210224
Glioblastoma is the most common and lethal primary brain malignancy. Despite major investments in research into glioblastoma biology and drug development, treatment remains limited and survival has not substantially improved beyond 1-2 years. Cancer stem cells (CSC) or glioma stem cells (GSC) refer to a population of tumor originating cells capable of self-renewal and differentiation. While controversial and challenging to study, evidence suggests that GCSs may result in glioblastoma tumor recur ...[more]