Neural and behavioral correlates of inhibitory control in youths with varying levels of irritability.

ABSTRACT:

Background

Irritability, a relatively lowered threshold for anger, is prevalent in typically and atypically developing youths. Inhibitory control, the ability to suppress behaviors counter to goals, is essential for regulating emotions, including anger. Understanding how irritability relates to behavioral and neural markers of inhibitory control may inform interventions.

Methods

Youths (N=52; mean age=13.78) completed a Flanker task on an iPad to measure behavioral correlates of inhibitory control; a subsample (n=19; mean age=13.21) additionally completed a similar task while undergoing fMRI acquisition to evaluate inhibitory control on a neural level. Irritability was measured using the Affective Reactivity Index. Associations between irritability and inhibitory control wer

SUBMITTER: Liuzzi MT 

PROVIDER: S-EPMC7945044 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature