Ontology highlight
ABSTRACT:
SUBMITTER: Hurskainen M
PROVIDER: S-EPMC7946947 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Hurskainen Maria M Mižíková Ivana I Cook David P DP Andersson Noora N Cyr-Depauw Chanèle C Lesage Flore F Helle Emmi E Renesme Laurent L Jankov Robert P RP Heikinheimo Markku M Vanderhyden Barbara C BC Thébaud Bernard B
Nature communications 20210310 1
During late lung development, alveolar and microvascular development is finalized to enable sufficient gas exchange. Impaired late lung development manifests as bronchopulmonary dysplasia (BPD) in preterm infants. Single-cell RNA sequencing (scRNA-seq) allows for assessment of complex cellular dynamics during biological processes, such as development. Here, we use MULTI-seq to generate scRNA-seq profiles of over 66,000 cells from 36 mice during normal or impaired lung development secondary to hy ...[more]