Ontology highlight
ABSTRACT: Background
Coronavirus disease 2019 (COVID-19) is a potentially fatal disease that is of great global public health concern.Objective
We explored the clinical management of inpatients with COVID-19 in Italy.Methods
A self-administered survey was sent by email to Italian physicians caring for adult patients with COVID-19. A panel of experts was selected according to their clinical curricula and their responses were analyzed.Results
A total of 1,215 physicians completed the survey questionnaire (17.4% response rate). Of these, 188 (15.5%) were COVID-19 experts. Chest computed tomography was the most used method to detect and monitor COVID-19 pneumonia. Most of the experts managed acute respiratory failure with CPAP (56.4%), high flow nasal cannula (18.6%), and non-invasive mechanical ventilation (8%), while an intensivist referral for early intubation was requested in 17% of the cases. Hydroxychloroquine was prescribed as an antiviral in 90% of cases, both as monotherapy (11.7%), and combined with protease inhibitors (43.6%) or azithromycin (36.2%). The experts unanimously prescribed low-molecular-weight heparin to patients with severe COVID-19 pneumonia, and half of them (51.6%) used a dose higher than standard. The respiratory burden in patients who survived the acute phase was estimated as relevant in 28.2% of the cases, modest in 39.4%, and negligible in 9%.Conclusions
In our survey some major topics, such as the role of non-invasive respiratory support and drug treatments, show disagreement between experts, likely reflecting the absence of high-quality evidence studies. Considering the significant respiratory sequelae reported following COVID-19, proper respiratory and physical therapy programs should be promptly made available.
SUBMITTER: Attanasi M
PROVIDER: S-EPMC7949238 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Attanasi Marina M Pasini Simone S Caronni Antonio A Pellegrino Giulia Michela GM Faverio Paola P Di Pillo Sabrina S Cimino Matteo Maria MM Cipolla Giuseppe G Chiarelli Francesco F Centanni Stefano S Sferrazza Papa Giuseppe Francesco GF
Respiration; international review of thoracic diseases 20200805 8
<h4>Background</h4>Coronavirus disease 2019 (COVID-19) is a potentially fatal disease that is of great global public health concern.<h4>Objective</h4>We explored the clinical management of inpatients with COVID-19 in Italy.<h4>Methods</h4>A self-administered survey was sent by email to Italian physicians caring for adult patients with COVID-19. A panel of experts was selected according to their clinical curricula and their responses were analyzed.<h4>Results</h4>A total of 1,215 physicians compl ...[more]