Ontology highlight
ABSTRACT:
SUBMITTER: Zimmermann J
PROVIDER: S-EPMC7949252 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Zimmermann Johannes J Kaleta Christoph C Waschina Silvio S
Genome biology 20210310 1
Genome-scale metabolic models of microorganisms are powerful frameworks to predict phenotypes from an organism's genotype. While manual reconstructions are laborious, automated reconstructions often fail to recapitulate known metabolic processes. Here we present gapseq ( https://github.com/jotech/gapseq ), a new tool to predict metabolic pathways and automatically reconstruct microbial metabolic models using a curated reaction database and a novel gap-filling algorithm. On the basis of scientifi ...[more]