Ontology highlight
ABSTRACT:
SUBMITTER: Shankar M
PROVIDER: S-EPMC7953150 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Shankar Madhu M Uwamahoro Nathalie N Backman Emelie E Holmberg Sandra S Niemiec Maria Joanna MJ Roth Johannes J Vogl Thomas T Urban Constantin F CF
Frontiers in immunology 20210226
Intra-abdominal infection (peritonitis) is a leading cause of severe disease in surgical intensive care units, as over 70% of patients diagnosed with peritonitis develop septic shock. A critical role of the immune system is to return to homeostasis after combating infection. S100A8/A9 (calprotectin) is an antimicrobial and pro-inflammatory protein complex used as a biomarker for diagnosis of numerous inflammatory disorders. Here we describe the role of S100A8/A9 in inflammatory collateral tissue ...[more]