Ontology highlight
ABSTRACT:
SUBMITTER: Forrester SJ
PROVIDER: S-EPMC7954131 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Forrester Steven J SJ Xu Qian Q Kikuchi Daniel S DS Okwan-Duodu Derick D Campos Ana Carolina AC Faidley Elizabeth A EA Zhang Guogang G Lassègue Bernard B Sadikot Ruxana T RT Griendling Kathy K KK Hernandes Marina S MS
Clinical science (London, England : 1979) 20190125 2
Acute respiratory distress syndrome (ARDS) in a deadly disease that can be brought on by endotoxins such as lipopolysaccharide (LPS). ARDS is characterized by vascular permeability, a severe inflammatory response, lung leukocyte infiltration, and resultant lung edema. Polymerase δ-interacting protein 2 (Poldip2) is a novel regulator of blood-brain barrier permeability; however, its role in regulating lung permeability and vascular inflammation is unknown. Here, the role of Poldip2 in regulating ...[more]