Ontology highlight
ABSTRACT:
SUBMITTER: Rodin AS
PROVIDER: S-EPMC7956201 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Rodin Andrei S AS Gogoshin Grigoriy G Hilliard Seth S Wang Lei L Egelston Colt C Rockne Russell C RC Chao Joseph J Lee Peter P PP
International journal of molecular sciences 20210226 5
Cancer immunotherapy, specifically immune checkpoint blockade, has been found to be effective in the treatment of metastatic cancers. However, only a subset of patients achieve clinical responses. Elucidating pretreatment biomarkers predictive of sustained clinical response is a major research priority. Another research priority is evaluating changes in the immune system before and after treatment in responders vs. nonresponders. Our group has been studying immune networks as an accurate reflect ...[more]