The Effects of Naringenin on miRNA-mRNA Profiles in HepaRG Cells.
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ABSTRACT:
SUBMITTER: Fan W
PROVIDER: S-EPMC7956767 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
The Effects of Naringenin on miRNA-mRNA Profiles in HepaRG Cells.
Fan Weiyang W Shi Rui R Guan Minyi M Chen Pan P Wu Hao H Su Weiwei W Wang Yonggang Y Li Peibo P
International journal of molecular sciences 20210225 5
Naringenin, a natural flavonoid widely found in citrus fruits, has been reported to possess anti-oxidant, anti-inflammatory, and hepatoprotective properties as a natural dietary supplement. However, the regulatory mechanism of naringenin in human liver remains unclear. In the present study, messenger RNA sequencing (mRNA-seq), microRNA sequencing (miRNA-seq), and real-time qPCR were used to distinguish the expression differences between control and naringenin-treated HepaRG cells. We obtained 10 ...[more]
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