Ontology highlight
ABSTRACT:
SUBMITTER: Koivunen J
PROVIDER: S-EPMC7960628 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Koivunen Jarkko J Tu Hongmin H Kemppainen Antti A Anbazhagan Padmanabhan P Finnilä Mikko A MA Saarakkala Simo S Käpylä Jarmo J Lu Ning N Heikkinen Anne A Juffer André H AH Heino Jyrki J Gullberg Donald D Pihlajaniemi Taina T
Cell and tissue research 20201211 3
Collagen XIII is a conserved transmembrane collagen mainly expressed in mesenchymal tissues. Previously, we have shown that collagen XIII modulates tissue development and homeostasis. Integrins are a family of receptors that mediate signals from the environment into the cells and vice versa. Integrin α11β1 is a collagen receptor known to recognize the GFOGER (O=hydroxyproline) sequence in collagens. Interestingly, collagen XIII and integrin α11β1 both have a role in the regulation of bone homeos ...[more]