Ontology highlight
ABSTRACT:
SUBMITTER: Fujii Y
PROVIDER: S-EPMC7966737 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Fujii Yuki Y Koizumi Wataru C WC Imai Taichi T Yokobori Megumi M Matsuo Tomohiro T Oka Kotaro K Hotta Kohji K Okajima Takaharu T
Communications biology 20210316 1
During the developmental processes of embryos, cells undergo massive deformation and division that are regulated by mechanical cues. However, little is known about how embryonic cells change their mechanical properties during different cleavage stages. Here, using atomic force microscopy, we investigated the stiffness of cells in ascidian embryos from the fertilised egg to the stage before gastrulation. In both animal and vegetal hemispheres, we observed a Rho kinase (ROCK)-independent cell stif ...[more]