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Extracellular amoebal-vesicles: potential transmission vehicles for respiratory viruses.


ABSTRACT: Human respiratory syncytial virus (RSV) is a major cause of acute respiratory tract infections in children and immunocompromised adults worldwide. Here we report that amoebae-release respirable-sized vesicles containing high concentrations of infectious RSV that persisted for the duration of the experiment. Given the ubiquity of amoebae in moist environments, our results suggest that extracellular amoebal-vesicles could contribute to the environmental persistence of respiratory viruses, including potential resistance to disinfection processes and thereby offering novel pathways for viral dissemination and transmission.

SUBMITTER: Dey R 

PROVIDER: S-EPMC7969602 | biostudies-literature |

REPOSITORIES: biostudies-literature

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2017-03-31 | GSE79282 | GEO