AAA+ ATPases: structural insertions under the magnifying glass.
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ABSTRACT:
SUBMITTER: Jessop M
PROVIDER: S-EPMC7973254 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Publications
AAA+ ATPases: structural insertions under the magnifying glass.
Jessop Matthew M Felix Jan J Gutsche Irina I
Current opinion in structural biology 20201124
AAA+ ATPases are a diverse protein superfamily which power a vast number of cellular processes, from protein degradation to genome replication and ribosome biogenesis. The latest advances in cryo-EM have resulted in a spectacular increase in the number and quality of AAA+ ATPase structures. This abundance of new information enables closer examination of different types of structural insertions into the conserved core, revealing discrepancies in the current classification of AAA+ modules into cla ...[more]
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