Ontology highlight
ABSTRACT:
SUBMITTER: Zhang X
PROVIDER: S-EPMC7975697 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Zhang Xudong X Xu Xiaoliang X Zhang Zechuan Z Xue Cailin C Kong Zhijun Z Wu Siyuan S Yun Xiao X Fu Yue Y Zhu Chunfu C Qin Xihu X
International journal of biological sciences 20210208 3
Long noncoding RNAs (LncRNAs) are emerging as crucial regulators in the pathophysiological process of various tumors, including HCC. Here, we identify a novel lncRNA Linc-KILH (KRT19 interacting long noncoding RNA in hepatocellular carcinoma), which is significantly up-regulated in HCC tissues and positively correlated with larger tumor size, severer microvascular invasion, more intrahepatic metastasis and decreased survival of HCC patients. Silence of Linc-KILH remarkably inhibited the prolifer ...[more]