Normative Data for Myocardial Native T1 and Extracellular Volume Fraction in Children.

ABSTRACT:

Purpose

To establish normative data for myocardial T1, including extracellular volume (ECV) fraction, in healthy children.

Materials and methods

In this retrospective, single-center study, T1 mapping data were collected from 48 healthy pediatric patients (14 years ± 3 [standard deviation]; range, 9-18 years; 27 of 48 [56%] male) referred for cardiac screening 1.5-T MRI between 2014 and 2017. T1 relaxometry was performed using a 5(number of heartbeats [nHB])3 modified Look-Locker inversion recovery (MOLLI) sequence, where nHB was three to five heartbeats depending on the heart rate, and was repeated 15 minutes following the administration of 0.2 mmol per kilogram of body weight of gadobenate dimeglumine, with 19 patients receiving contrast material. T1 values were calculated

SUBMITTER: Pagano JJ 

PROVIDER: S-EPMC7977704 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature