Ontology highlight
ABSTRACT:
SUBMITTER: Muller SJ
PROVIDER: S-EPMC7979664 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Müller Sebastian J SJ Weigl Franziska F Bezold Carina C Bächer Christian C Albrecht Krystyna K Gekle Stephan S
Biomechanics and modeling in mechanobiology 20201120 2
In the emerging field of 3D bioprinting, cell damage due to large deformations is considered a main cause for cell death and loss of functionality inside the printed construct. Those deformations, in turn, strongly depend on the mechano-elastic response of the cell to the hydrodynamic stresses experienced during printing. In this work, we present a numerical model to simulate the deformation of biological cells in arbitrary three-dimensional flows. We consider cells as an elastic continuum accor ...[more]