Ontology highlight
ABSTRACT:
SUBMITTER: F Dudas E
PROVIDER: S-EPMC7985572 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
F Dudás Erika E Puglisi Rita R Korn Sophie Marianne SM Alfano Caterina C Bellone Maria Laura ML Piaz Fabrizio Dal FD Kelly Geoff G Monaca Elisa E Schlundt Andreas A Schwalbe Harald H Pastore Annalisa A
Biomolecular NMR assignments 20210323 2
As part of an International consortium aiming at the characterization by NMR of the proteins of the SARS-CoV-2 virus, we have obtained the virtually complete assignment of the backbone atoms of the non-structural protein nsp9. This small (12 kDa) protein is encoded by ORF1a, binds to RNA and seems to be essential for viral RNA synthesis. The crystal structures of the SARS-CoV-2 protein and other homologues suggest that the protein is dimeric as also confirmed by analytical ultracentrifugation an ...[more]