Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis.

ABSTRACT:

Objective

To describe the comparative efficacy of drug and non-drug interventions for reducing symptoms of depression in people with dementia who experience depression as a neuropsychiatric symptom of dementia or have a diagnosis of a major depressive disorder.

Design

Systematic review and meta-analysis.

Data sources

Medline, Embase, the Cochrane Library, CINAHL, PsycINFO, and grey literature between inception and 15 October 2020.

Eligibility criteria for study selection

Randomised trials comparing drug or non-drug interventions with usual care or any other intervention targeting symptoms of depression in people with dementia.

Main outcome measures

Pairs of reviewers screened studies, abstracted aggregate level data, and appraised risk of bias with the C

SUBMITTER: Watt JA 

PROVIDER: S-EPMC7988455 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature