Ontology highlight
ABSTRACT:
SUBMITTER: Yu X
PROVIDER: S-EPMC7992161 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Yu Xiaodan X Li Li L Sun Shiwei S Chang Aiping A Dai Xiaoyun X Li Hui H Wang Yinglu Y Zhu Hu H
ACS omega 20210312 11
Bacterial quorum sensing (QS) is anticipated as a new potential target for the development of antimicrobial drugs. An anti-QS substance against <i>Chromobacterium violaceum</i> CV026 and <i>Pseudomonas aeruginosa</i> PA01 has been isolated and purified from the crude extracts of the marine fungus <i>Penicillium chrysogenum</i> DXY-1, and the accurate structure was identified as cyclo(l-Tyr-l-Pro). This cyclic dipeptide at sub-minimum inhibitory concentration can decrease the QS-regulated violace ...[more]