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ABSTRACT: Background
Face-to-face procedures have been postponed during COVID-19 pandemic. We aim to evaluate the impact of onabotulinumtoxinA follow-up delay in migraine during COVID-19 pandemic.Methods
Subjective worsening, intensity of migraine attacks, and frequency of headache and migraine were retrospectively compared between patients with unmodified and interrupted onabotulinumtoxinA follow-up in Headache Units.Results
We included 67 patients with chronic migraine or high-frequency episodic migraine under onabotulinumtoxinA treatment, 65 (97.0%) female, 44.5 ± 12.1 years old. Treatment administration was voluntarily delayed in 14 (20.9%) patients and nine (13.4%) were unable to continue follow-up. Patients with uninterrupted follow-up during lockdown presented 7.6 and 8.1 less monthly days with headache (adjusted p = 0.017) and migraine attacks (adjusted p = 0.009) compared to patients whose follow-up was interrupted, respectively.Conclusion
Involuntary delay of onabotulinumtoxinA follow-up in patients with migraine due to COVID-19 pandemic was associated with a higher frequency of headache and migraine attacks. Safe administration of onabotulinumtoxinA during lockdown should be promoted.
SUBMITTER: Gonzalez-Martinez A
PROVIDER: S-EPMC7994064 | biostudies-literature | 2021 Dec
REPOSITORIES: biostudies-literature
Gonzalez-Martinez Alicia A Planchuelo-Gómez Álvaro Á Guerrero Ángel L ÁL García-Azorín David D Santos-Lasaosa Sonia S Navarro-Pérez María Pilar MP Odriozola-González Paula P Irurtia María Jesús MJ Quintas Sonia S de Luis-García Rodrigo R Gago-Veiga Ana Beatriz AB
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20210326 12
<h4>Background</h4>Face-to-face procedures have been postponed during COVID-19 pandemic. We aim to evaluate the impact of onabotulinumtoxinA follow-up delay in migraine during COVID-19 pandemic.<h4>Methods</h4>Subjective worsening, intensity of migraine attacks, and frequency of headache and migraine were retrospectively compared between patients with unmodified and interrupted onabotulinumtoxinA follow-up in Headache Units.<h4>Results</h4>We included 67 patients with chronic migraine or high-fr ...[more]