COVID-19 Vaccine Failure in a Patient with Multiple Sclerosis on Ocrelizumab.
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ABSTRACT:
SUBMITTER: Chilimuri S
PROVIDER: S-EPMC8002140 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
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COVID-19 Vaccine Failure in a Patient with Multiple Sclerosis on Ocrelizumab.
Chilimuri Sridhar S Mantri Nikhitha N Gongati Sudharsan S Zahid Maleeha M Sun Haozhe H
Vaccines 20210304 3
Vaccines will play a key role in ending the COVID-19 pandemic. Vaccination against infections remains an important part of the management of patients with multiple sclerosis. However, there are limited data about the safety and efficacy of the currently available COVID-19 mRNA vaccines in patients with multiple sclerosis receiving concurrent immunosuppressive therapies. Patients on B cell depleting therapy such as ocrelizumab have an attenuated vaccine response. We report the first case of COVID ...[more]
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