Unknown

Dataset Information

0

Evidence for current circulation of an ancient West Nile virus strain (NY99) in Brazil.

ABSTRACT: In Brazil, West Nile virus (WNV) was first detected, in 2018, in horses with neurological disease. We report the first case of WNV infection in a horse from Ceará state and the complete genome sequence of an isolate from Espírito Santo state. Both infections occurred in 2019. WNV was isolated from the tissues of a horse with neurological signs in Espírito Santo and sequenced by MiSeq. Phylogenetic analysis revealed that the isolate belongs to lineage 1a, clustering with the NY99 strain, a strain that has not circulated in the USA since 2005. Our findings reinforce the hypothesis that WNV has been silently circulating in Brazil for many years.

SUBMITTER: Siconelli MJL 

PROVIDER: S-EPMC8008906 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

<h4>Introduction</h4>In Brazil, West Nile virus (WNV) was first detected, in 2018, in horses with neurological disease.<h4>Aim</h4>We report the first case of WNV infection in a horse from Ceará state and the complete genome sequence of an isolate from Espírito Santo state. Both infections occurred in 2019.<h4>Methods</h4>WNV was isolated from the tissues of a horse with neurological signs in Espírito Santo and sequenced by MiSeq.<h4>Results</h4>Phylogenetic analysis revealed that the isolate be  ...[more]

Similar Datasets

Genomics West Nile virus strain:NY99
| PRJNA281547 | ENA
Genomics West Nile virus strain:NY99
| PRJNA311123 | ENA
Unknown Serological evidence of widespread circulation of West Nile virus and other flaviviruses in equines of the Pantanal, Brazil.
| S-EPMC3923745 | biostudies-literature
Unknown West Nile Virus in Brazil.
| S-EPMC8308589 | biostudies-literature
Unknown West Nile virus in Mexico: evidence of widespread circulation since July 2002.
| S-EPMC3034333 | biostudies-literature
Unknown Retrospective Investigation in Horses with Encephalitis Reveals Unnoticed Circulation of West Nile Virus in Brazil.
| S-EPMC9316658 | biostudies-literature
Unknown Horizontal and vertical transmission of West Nile virus genotype NY99 by Culex salinarius and genotypes NY99 and WN02 by Culex tarsalis.
| S-EPMC3247122 | biostudies-literature
Unknown West Nile virus lineage 2 in Romania, 2015-2016: co-circulation and strain replacement.
| S-EPMC6203995 | biostudies-literature
Unknown Rapid determination of HLA B*07 ligands from the West Nile virus NY99 genome.
| S-EPMC2631750 | biostudies-other
Unknown Plasticity of a critical antigenic determinant in the West Nile virus NY99 envelope protein domain III.
| S-EPMC4969113 | biostudies-literature