Association of a Shortened Duration of Adjuvant Chemotherapy With Overall Survival Among Individuals With Stage III Colon Cancer.

ABSTRACT:

Importance

Several real-world oncology studies have produced findings that contradict those from randomized clinical trials. Such disparities may be associated with methodological shortcomings.

Objective

To examine the association between a shortened duration of adjuvant chemotherapy among individuals with stage III colon cancer using real-world data.

Design, setting, and participants

This comparative effectiveness study included individuals diagnosed with stage III colon cancer between January 2004 and December 2015 who initiated adjuvant chemotherapy at oncology clinics within the province of Alberta, Canada. Patients were identified through record linkage of various administrative databases and were followed up until September 2017. Eligibility criteria were modele

SUBMITTER: Boyne DJ 

PROVIDER: S-EPMC8010592 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature