Ontology highlight
ABSTRACT:
SUBMITTER: Wang T
PROVIDER: S-EPMC8011994 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Wang Tietao T Hu Zhaoyu Z Du Xiao X Shi Yue Y Dang Jing J Lee Mijoon M Hesek Dusan D Mobashery Shahriar S Wu Min M Liang Haihua H
Molecular microbiology 20200422 2
The human pathogen Pseudomonas aeruginosa harbors three paralogous zinc proteases annotated as AmpD, AmpDh2, and AmpDh3, which turn over the cell wall and cell wall-derived muropeptides. AmpD is cytoplasmic and plays a role in the recycling of cell wall muropeptides, with a link to antibiotic resistance. AmpDh2 is a periplasmic soluble enzyme with the former anchored to the inner leaflet of the outer membrane. We document, herein, that the type VI secretion system locus II (H2-T6SS) of P. aerugi ...[more]