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Acute cerebellar ataxia and myoclonus with or without opsoclonus: a para-infectious syndrome associated with COVID-19.


ABSTRACT:

Background and purpose

Patients with COVID-19 can have central or peripheral neurological manifestations.

Methods

The cases of two patients with acute cerebellar ataxia and myoclonus associated with COVID-19 are reported (with Video S1) and five previously reported patients are discussed.

Results

Acute cerebellar ataxia and myoclonus started between 10 days and 6 weeks after the first manifestations of COVID-19. Opsoclonus or ocular flutter was present in four patients. Patients were treated with intravenous immunoglobulins and/or steroids except for one patient, resulting in a striking improvement within a week.

Conclusion

Acute cerebellar ataxia and myoclonus with or without opsoclonus belongs to the wide spectrum of neurological manifestations associated with COVID-19. It is important to recognize this possible manifestation since early treatment allows for rapid recovery.

SUBMITTER: Foucard C 

PROVIDER: S-EPMC8013847 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature

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Publications

Acute cerebellar ataxia and myoclonus with or without opsoclonus: a para-infectious syndrome associated with COVID-19.

Foucard Cendrine C   San-Galli Aurore A   Tarrano Clément C   Chaumont Hugo H   Lannuzel Annie A   Roze Emmanuel E  

European journal of neurology 20211001 10


<h4>Background and purpose</h4>Patients with COVID-19 can have central or peripheral neurological manifestations.<h4>Methods</h4>The cases of two patients with acute cerebellar ataxia and myoclonus associated with COVID-19 are reported (with Video S1) and five previously reported patients are discussed.<h4>Results</h4>Acute cerebellar ataxia and myoclonus started between 10 days and 6 weeks after the first manifestations of COVID-19. Opsoclonus or ocular flutter was present in four patients. Pat  ...[more]

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