Micellization of Sequence-Controlled Polyurethane Ionomers in Mixed Aqueous Solvents.

ABSTRACT: While the impact of compositional parameters such as block length and ionic content on the micellization of (polymeric) amphiphiles is widely investigated, the influence of monomer sequence has received far less attention until recently. Here, we report the synthesis of two sequence-controlled polyurethane ionomers (PUIs) prepared via a stepwise coupling-deprotection strategy, and compare their solution association in aqueous-organic mixtures. The two PUIs are highly similar in mass and overall composition, yet differ markedly in the sequence of building blocks. PUI-A2 comprises a polytetrahydrofuran (pTHF) block connected to an alternation of isophorone diamine (IPDA) and dimethylolpropionic acid (DMPA) units that together are also arranged in a blockwise manner. The result is a ma

SUBMITTER: Timmers EM 

PROVIDER: S-EPMC8016144 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature