Ontology highlight
ABSTRACT:
SUBMITTER: Martinez-Matias N
PROVIDER: S-EPMC8016984 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Martínez-Matías Nelson N Chorna Nataliya N González-Crespo Sahily S Villanueva Lilliam L Montes-Rodríguez Ingrid I Melendez-Aponte Loyda M LM Roche-Lima Abiel A Carrasquillo-Carrión Kelvin K Santiago-Cartagena Ednalise E Rymond Brian C BC Babu Mohan M Stagljar Igor I Rodríguez-Medina José R JR
Scientific reports 20210401 1
Functional analysis of the Mtl1 protein in Saccharomyces cerevisiae has revealed that this transmembrane sensor endows yeast cells with resistance to oxidative stress through a signaling mechanism called the cell wall integrity pathway (CWI). We observed upregulation of multiple heat shock proteins (HSPs), proteins associated with the formation of stress granules, and the phosphatase subunit of trehalose 6-phosphate synthase which suggests that mtl1Δ strains undergo intrinsic activation of a non ...[more]