Ontology highlight
ABSTRACT:
SUBMITTER: Ferdoushi A
PROVIDER: S-EPMC8017010 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Ferdoushi Aysha A Griffin Nathan N Marsland Mark M Xu Xiaoyue X Faulkner Sam S Gao Fangfang F Liu Hui H King Simon J SJ Denham James W JW van Helden Dirk F DF Jobling Phillip P Jiang Chen Chen CC Hondermarck Hubert H
Scientific reports 20210401 1
Pancreatic cancer is a highly aggressive malignancy characterized by poor survival, recurrence after surgery and resistance to therapy. Nerves infiltrate the microenvironment of pancreatic cancers and contribute to tumor progression, however the clinicopathological significance of tumor innervation is unclear. In this study, the presence of nerves and their cross-sectional size were quantified by immunohistochemistry for the neuronal markers S-100, PGP9.5 and GAP-43 in a series of 99 pancreatic ...[more]