Shocked quartz in distal ejecta from the Ries impact event (Germany) found at ~ 180 km distance, near Bernhardzell, eastern Switzerland.
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ABSTRACT:
SUBMITTER: Holm-Alwmark S
PROVIDER: S-EPMC8018947 | biostudies-literature |
REPOSITORIES: biostudies-literature
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Project description:Impact ejecta are important references to establish regional and global stratigraphy of planetary bodies. Canonical views advocate radial distributions of distal ejecta with respect to the source crater, and their trajectories are significantly deflected on fast-rotating bodies. The Hokusai crater on Mercury formed a peculiar ray that features a hyperbola shape, and the sharp swerve of orientation was interpreted as a sign of a faster planetary rotation in the near past. Here, we show that this ray was not caused by a hypothesized larger Coriolis force, but due to abruptly-steepened ejection angles. Heterogeneous shock impedances of pre-impact impactor and/or target, such as topographic undulations, affect local propagation paths of shock and rarefaction waves, causing sudden changes of ejection angles. Distal ejecta with non-radial distributions are an inherent product of planetary impacts, and their unobvious provenances could mislead stratigraphic interpretations and hamper age estimations based on spatial densities of impact craters.
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Project description:The review provides a systematic overview of the state of quantitative research on teaching and learning characteristics during school closures due to corona. The review comprises 97 online surveys conducted between 24th of March 2020 and 11th of November 2020 and covering 255,955 cases (students, parents, teachers, school leaders etc.). The analysis and synthesis of the findings was carried out along two models, the phase model of the research process and the "integrative model on distance education". The review makes clear that central aspects of teaching and learning during corona-based school closures in Spring 2020, such as distance learning characteristics (e.g. quality dimensions), student characteristics (e.g. self-sufficiency) and characteristics of home resources for learning (e.g. parental support) have already been the object of many surveys. The school situation during the corona pandemic is therefore no longer an unexplored phenomenon. Rather, the scientific ethos of researchers in this field demands that the current state of research needs to be considered in their work. The review presented here is intended to facilitate this task by not only listing the existing surveys, but also synthesizing their central findings. In addition, the review provides a relevant information basis for decisions and action in politics, administration and school practice. At the same time, the review warns against an unreflected adoption of the findings by critically discussing the scientific quality of the surveys.
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Project description:BackgroundEnergy cooperatives are a prominent and common form of community energy. Community energy has the potential to increase actor diversity and local acceptance of renewable energies and has therefore been highlighted to be conducive to energy transitions. While research has recognized the importance of both the national and the local governance levels for community energy, it remains unclear how these two levels are related. Against this backdrop, this paper investigates how municipalities support energy cooperatives at the local level and how this support is related to national context conditions.MethodsThe study takes a quantitative approach using own survey data from Germany and Switzerland. Based on a typology of municipal support, we compare limiting factors and municipal support for energy cooperatives between the two countries as well as between energy cooperatives with and without municipal membership. By means of this two-tiered comparison, we analyze how municipal support is related to national contexts, specifically regarding national energy policies, and to municipal involvement in the cooperatives.ResultsOur analysis shows that municipal support can benefit energy cooperatives as it addresses some of the major limiting factors for energy cooperatives in Germany and Switzerland. However, our data suggest that municipalities only specifically address cooperatives' limitations with support measures if they are a member in the cooperative. This indicates that organizational involvement of a municipality in energy cooperatives leads to a more targeted support compared to non-members and thus is beneficial to meet the specific cooperatives' challenges due to national energy policy.ConclusionsCooperatives can benefit from municipal support, especially if the municipality is a cooperative member. Municipal support is likely to become even more important for energy cooperatives in the future, due to reduced national support for renewable energies in Germany and Switzerland. On their part, municipalities can benefit from collaborating with energy cooperatives, as they gain an additional instrument to implement municipal energy policy. Hence, supporting and seeking membership in energy cooperatives appear to be adequate strategies for municipalities to foster a decentralized energy transition.
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Project description:Background and aimsThe need for patient safety through consistent diagnostic performance has increasingly been brought into focus during the last two decades. Around the globe operational efficiency of diagnostic laboratories plays a key role in satisfying this need, which has impressively been shown during the recent months of the SARS-CoV‑2 pandemic. On a global level, however, there has been a lack to collate and benchmark data for diagnostic laboratories. The goals of this study were to design and pilot a questionnaire addressing key aspects of diagnostic laboratory management.MethodsThe questionnaire was designed using an iterative process and taking into consideration information that could be extracted from the literature, author experience and feedback from informal focus groups of laboratory professionals. The resulting tool consisted of 50 items, either relating to general information or more specifically addressing the topics of "operational performance", "integrated clinical care performance", and "financial sustainability". A limited number of laboratories were surveyed to be able to further improve the newly developed tool and motivate the global laboratory community to participate in further benchmarking activity.Results and conclusionAltogether, 65 laboratories participated in the survey, 42 were hospital laboratories and 23 were commercial laboratories. Potential for further improvement and standardization became apparent across the board, e.g. use of IT for order management, auto-validation, or turn-around time (TAT) monitoring. Notably, a gap was identified regarding services provided to physicians, in particular "reflexive test suggestions", "proactive consultation on complex cases", and "diagnostic pathways guidance", which were only provided by about two thirds of laboratories. Concordantly, within-laboratory TAT (Lab TAT) was monitored by about 80% of respondents, while sample-to-result TAT, which is arguably the TAT most relevant to clinicians, was only monitored by 32% of respondents. Altogether, the need for stronger integration of the laboratory into the clinical care process became apparent and should be a main trajectory of future laboratory management.
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Project description:ImportanceBiologics account for a substantial proportion of health care expenditures. Their costs have been projected to reach US $452 billion in global spending by 2022. Given recent expiration of patent protection of biologics, a shift toward greater follow-on competition among biosimilars would be expected that would allow greater uptake and lower drug costs.ObjectiveTo assess uptake and prices of biosimilars in the US compared with 2 European countries (Germany and Switzerland) with national mechanisms for drug price negotiation.Design, setting, and participantsIn this cohort study, biologics and biosimilars that were approved in the US, Germany, and Switzerland until August 2020 were identified. Prices and sales data were extracted from public and commercial databases for the years 2011 to 2020. Data were analyzed from August 1, 2021, to February 28, 2022.Main outcomes and measuresDescriptive statistics were used to show temporal trends in the uptake of biosimilars and relative prices compared with those of reference products (ie, biologic agents) for each country. Descriptive analysis was also performed to compare the uptake of biosimilars between the 3 countries limited to biologics that have biosimilars on the market in all countries. To test if biosimilar awareness in each country increased over the last decade, a linear least squares regression was applied.ResultsThe study cohort included 15 biosimilars and 6 biologics for the US, 52 biosimilars and 15 biologics for Germany, and 28 biosimilars and 13 biologics for Switzerland. Uptake of biosimilars increased over time in all countries. On average, the biosimilar market share at launch was highest in Germany; however, it increased at the fastest rate in the US. Monthly treatment costs of biosimilars in the US were a median of 1.94 (IQR, 1.78-2.44) and 2.74 (IQR, 1.91-3.46) higher than corresponding costs in Germany and Switzerland, respectively.Conclusions and relevanceThe findings of this cohort study suggest that more biosimilars have been marketed in Germany and Switzerland than in the US. Policies that counter anticompetitive practices in the US could allow biosimilars to enter the market sooner and could also lower health care costs with improved access. Awareness of biosimilars should be promoted to increase uptake of biosimilars globally.
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