Changes in local brain function in mild cognitive impairment due to semantic dementia.

ABSTRACT:

Aims

Mild cognitive impairment due to semantic dementia represents the preclinical stage, involving cognitive decline dominated by semantic impairment below the semantic dementia standard. Therefore, studying mild cognitive impairment due to semantic dementia may identify changes in patients before progression to dementia. However, whether changes in local functional activity occur in preclinical stages of semantic dementia remains unknown. Here, we explored local functional changes in patients with mild cognitive impairment due to semantic dementia using resting-state functional MRI.

Methods

We administered a battery of neuropsychological tests to twenty-two patients with mild cognitive impairment due to semantic dementia (MCI-SD group) and nineteen healthy controls (HC gro

SUBMITTER: Cui L 

PROVIDER: S-EPMC8025655 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature