Ontology highlight
ABSTRACT:
SUBMITTER: Ma H
PROVIDER: S-EPMC8027994 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Ma Huijuan H Peng Limin L Huang Chiung-Yu CY Fu Haoda H
Biometrika 20201119 1
Progression of chronic disease is often manifested by repeated occurrences of disease-related events over time. Delineating the heterogeneity in the risk of such recurrent events can provide valuable scientific insight for guiding customized disease management. In this paper, we propose a new sensible measure of individual risk of recurrent events and present a dynamic modeling framework thereof, which accounts for both observed covariates and unobservable frailty. The proposed modeling requires ...[more]