Ontology highlight
ABSTRACT:
SUBMITTER: Delcour M
PROVIDER: S-EPMC8028965 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Delcour Maxime M Olivier Paul P Chambon Caroline C Pansiot Julien J Russier Michaël M Liberge Martine M Xin Dong D Gestreau Christian C Alescio-Lautier Béatrice B Gressens Pierre P Verney Catherine C Barbe Mary F MF Baud Olivier O Coq Jacques-Olivier JO
Brain pathology (Zurich, Switzerland) 20110816 1
Perinatal brain injury including white matter damage (WMD) is highly related to sensory, motor or cognitive impairments in humans born prematurely. Our aim was to examine the neuroanatomical, functional and behavioral changes in adult rats that experienced prenatal ischemia (PI), thereby inducing WMD. PI was induced by unilateral uterine artery ligation at E17 in pregnant rats. We assessed performances in gait, cognitive abilities and topographical organization of maps, and neuronal and glial de ...[more]