Ontology highlight
ABSTRACT:
SUBMITTER: Fujiwara T
PROVIDER: S-EPMC8030911 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Fujiwara Takeshi T Hoshide Satoshi S Yano Yuichiro Y Kanegae Hiroshi H Kario Kazuomi K
Journal of clinical hypertension (Greenwich, Conn.) 20171105 12
The aim of this study was to compare the effect of morning and bedtime administration of valsartan/amlodipine combination therapy (80/5 mg) on nocturnal brachial and central blood pressure (BP) measured by ambulatory BP monitoring in patients with hypertension. This was a 16-week prospective, multicenter, randomized, open-label, crossover, noninferiority clinical trial. Patients underwent 24-hour ambulatory BP monitoring at randomization, at switching, and at the end of the study. Twenty-three p ...[more]