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Deformation and rupture of microcapsules flowing through constricted capillary.

ABSTRACT: The dynamics of deformable microcapsules flowing through constricted channels is relevant in target delivery of chemicals in physiological systems, porous media, microfluidic medical diagnostic devices and many other applications. In some situations, the microcapsules need to sustain the stress they are subjected to as they flow through constricted channels and in others, the stress may be the rupture trigger used to release the internal content. We experimentally investigate the flow of monodispersed gellan gum microcapsules through a constricted capillary tube by measuring the evolution of the pressure difference and flow visualization. The maximum pressure difference and capsule deformation is obtained for capsules with different diameter and shell thickness. We map the conditions, e.g. diameter and shell thickness, at which the capsule membrane ruptures during the flow, releasing its internal phase.

SUBMITTER: Leopercio BC

PROVIDER: S-EPMC8032800 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Deformation and rupture of microcapsules flowing through constricted capillary.

Leopércio Bruna C BC Michelon Mariano M Carvalho Marcio S MS

Scientific reports 20210408 1

The dynamics of deformable microcapsules flowing through constricted channels is relevant in target delivery of chemicals in physiological systems, porous media, microfluidic medical diagnostic devices and many other applications. In some situations, the microcapsules need to sustain the stress they are subjected to as they flow through constricted channels and in others, the stress may be the rupture trigger used to release the internal content. We experimentally investigate the flow of monodis ...[more]

PMID: 33833279

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