Ontology highlight
ABSTRACT:
SUBMITTER: Proctor RSJ
PROVIDER: S-EPMC8033566 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20210329 13
Minisci-type reactions constitute one of the most powerful methods for building up complexity around basic heteroarenes. The most desirable variants involve formal oxidative coupling of a C-H bond on each partner, leading back to the simplest possible starting materials. We herein disclose a method that enables such a coupling of linear amides and heteroarenes with full control of enantioselectivity at the newly formed stereocenter as well as site selectivity on both the heteroarene and the amid ...[more]