The role of interindividual licking received and dopamine genotype on later-life licking provisioning in female rat offspring.

ABSTRACT:

Introduction

Rat mothers exhibit natural variations in care that propagate between generations of female offspring. However, there is limited information on genetic variation that could influence this propagation.

Methods

We assessed early-life maternal care received by individual female rat offspring, later-life maternal care provisioning, and dopaminergic activity in the maternal brain in relation to naturally occurring genetic polymorphisms linked to the dopaminergic system. We also conducted a systematic analysis of other genetic variants potentially related to maternal behavior in our Long-Evans rat population.

Results

While we did not find a direct relationship between early-life licking received and later-life licking provisioning, this relationship was indirec

SUBMITTER: Lauby SC 

PROVIDER: S-EPMC8035462 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature