Ontology highlight
ABSTRACT:
SUBMITTER: Thirumalaisamy R
PROVIDER: S-EPMC8041731 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Thirumalaisamy R R Aroulmoji V V Iqbal Muhammad Nasir MN Deepa M M Sivasankar C C Khan Riaz R Selvankumar T T
Journal of molecular structure 20210413
<i>In-silico</i> anti-viral activity of <i>Hydroxychloroquine</i> (HCQ) and its Hyaluronic Acid-derivative (HA-HCQ) towards different SARS-CoV-2 protein molecular targets were studied. Four different SARS-CoV-2 proteins molecular target i.e., three different main proteases and one helicase were chosen for <i>In-silico</i> anti-viral analysis. The HA-HCQ conjugates exhibited superior binding affinity and interactions with all the screened SAR-CoV-2 molecular target proteins with the exception of ...[more]